Products related to Genomic:
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Genomic Politics : How the Revolution in Genomic Science Is Shaping American Society
A groundbreaking analysis of how the genomic revolution is transforming American society and creating new social divisions-some along racial lines-that promise to fundamentally shape American politics for years to come.The emergence of genomic science in the last quarter century has revolutionized medicine, the justice system, and our understanding of who we are.We use genomics to determine guilt and exonerate the falsely convicted; devise new medicines; test embryos; and discover our ethnic and national roots.One might think that, given these advances, most would favor the availability of genomic tools.Yet as Jennifer Hochschild explains in Genomic Politics, the uses of genomic science are both politically charged and hotly contested.After all, genomics might result in bioterrorism, a demand for "designer babies," or a revival of racial biology. Political divisions around genomics do not follow the usual left-right ideological divides that dominate most of American politics.Through four controversial innovations resulting from genomic science—medicines for heart disease approved for use by only African-Americans, on the grounds of genetic distinctiveness; use of DNA evidence in the criminal justice system; the search for one's roots through genetic ancestry; and the use of genetic tests in prenatal exams—Hochschild reveals how the phenomenon is polarizing America in novel ways.Advocates of genomic science argue that these applications will make life better, while opponents point out the potential for misuse—from racial profiling to "selecting out" fetuses that gene tests show to have conditions like Down syndrome.Hochschild's central message is that the divide hinges on answers to two questions: How significant are genetic factors in explaining human traits and behaviors? And what is the right balance between risk acceptance and risk avoidance for a society grappling with innovations arising from genomic science?Experts differ among themselves about who should make decisions about governing genomics' uses, and Americans as a whole trust almost no one to do so.A deeply researched and original analysis of the politics surrounding one of the signal issues of our times, this is essential reading for anyone interested in how the genetics revolution is shaping society.
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Genomic Surveillance and Pandemic Preparedness
Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied.Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness.Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity.A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed.Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines.Throughout this book, importance is placed on inference—moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness.
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Genomic and Molecular Cardiovascular Medicine
The Genomic and Molecular Cardiovascular Medicine largely focuses on pertinent genomic and molecular aspects of cardiovascular medicine relevant to all levels of clinical practice, from primary care to preventive healthcare.The book also focuses on practice applications of translational genomic and molecular developments and advances that impact on cardiovascular system structure and function.Each chapter is evidence-based and comprehensive, with in-depth, cutting-edge knowledge relevant to the practice of clinical cardiology and cardiovascular surgery.The book aims to fill a major gap of knowledge resource focused on genomic and molecular aspects of contemporary cardiovascular medicine and surgery practice. In view of scientific and technical complexities of the field, the book is written by a team of globally acknowledged experts in respective clinical, investigative, therapeutic and preventive aspects.The current practices within cardiovascular medicine and surgery offer excellent opportunity for genomic and molecular applications to achieve the high order effectiveness with maximum efficiency.
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Potential Pulses : Genetic and Genomic Resources
The fight against global hunger demands a fresh perspective.Lesser-known legumes, often called 'potential pulses', can play a pivotal role.These underutilized powerhouses, including adzuki bean, bambara groundnut, faba bean, cowpea, grass pea and horse gram, among others, are currently untapped resources.Their potential goes beyond their ability to thrive in harsh environments (caused by high temperature, drought, etc.) and fix nitrogen.With increased understanding of these legumes and their genetic and genomic potential, we can unlock a new world of sustainable and nutritious food sources.This book explores: The rich genetic diversity of potential pulses and its role in resilience.How advanced genomics can identify traits for improved yields, pest resistance, and climate adaptation.Strategies for conserving and utilizing these valuable genetic resources.Breeding programmes harnessing genetic potential to create next-generation pulse varieties.Focusing on the untapped genetic and genomic potential of these legumes, this book empowers researchers, breeders, and policymakers to unlock a new era of food and nutritional security.By leveraging the power of their genes, we can transform underutilized pulses into the nutritional heroes of tomorrow.
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Is a 10-0 victory against Morocco not very unworthy for a reigning world champion?
A 10-0 victory against any team is an impressive feat, regardless of their status as a reigning world champion. It demonstrates the skill and dominance of the winning team. While Morocco may not be considered a top-tier team, a 10-0 victory is still a significant achievement and should be celebrated by the winning team. It is a testament to their ability and should not be dismissed as unworthy simply because of the opponent.
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'DSDS winner'
The winner of DSDS, which stands for "Deutschland sucht den Superstar" (Germany seeks the superstar), is the contestant who receives the highest number of votes from the audience throughout the season. This winner is crowned the "Superstar" and receives a recording contract as well as the title of the show. DSDS is a popular German reality television show that follows a similar format to other singing competitions like American Idol. The winner of DSDS gains recognition and often goes on to have a successful music career.
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Who is standing at the podium?
The person standing at the podium is the keynote speaker for the event. They are typically an expert or a notable figure in the field related to the event's theme. The speaker's role is to deliver a speech or presentation to engage and inform the audience.
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What is a youth room podium?
A youth room podium is a raised platform or stage area within a youth room or space, typically used for various activities and events. It provides a designated area for youth to gather, perform, or engage in group discussions or presentations. The podium may be used for hosting youth-led activities, such as talent shows, workshops, or group meetings, and can serve as a focal point for the youth community within a church, school, or community center.
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The Applied Genomic Epidemiology Handbook : A Practical Guide to Leveraging Pathogen Genomic Data in Public Health
The Applied Genomic Epidemiology Handbook: A Practical Guide to Leveraging Pathogen Genomic Data in Public Health provides rationale, theory, and implementation guidance to help public health practitioners incorporate pathogen genomic data analysis into their investigations.During the SARS-CoV-2 pandemic, viral whole genome sequences were generated, analyzed, and shared at an unprecedented scale.This wealth of data posed both tremendous opportunities and challenges; the data could be used to support varied parts of the public health response but could be hard for much of the public health workforce to analyze and interpret, given a historical lack of experience working with pathogen genomic data. This book addresses that gap. Structured into eight wide-ranging chapters, this book describes how the overlapping timescales of pathogen evolution and infection transmission enable exploration of epidemiologic dynamics from pathogen sequence data.Different approaches to sampling and genomic data inclusion are presented for different types of epidemiologic investigations.To support epidemiologists in diving into pathogen genomic data analysis, this book also introduces the analytic tools and approaches that are readily used in public health departments and presents case studies to show step-by-step how genomic data are used and evaluated in disease investigations. Despite the breadth of scientific literature that uses pathogen genomic data to investigate disease dynamics, there remains little practical guidance to help applied epidemiologists build their ability to explore epidemiologic questions with pathogen genomic data.This handbook was written to serve as that guide. Including case studies, common methods, and software tools, this book will be of great interest to public health microbiologists or lab directors, bioinformaticians, epidemiologists, health officers, academics, as well as students working in a public health context.
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Diagnostic Immunohistochemistry : Theranostic and Genomic Applications
Through five well-regarded editions, Dr. David Dabbs' Diagnostic Immunohistochemistry has set the standard for concise, complete, guidance on the use and interpretation of immunohistochemical stains.The 6th Edition continues this tradition of excellence, bringing you fully up to date with all aspects of this dynamic field.Easy to use and understand, this practical resource distills the large body of information on immunohistochemistry into a single, convenient reference that is invaluable for today's surgical pathologists. Covers all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Includes the latest grading schemes in several organs along with new antibodies to cover more genomic immunohistochemistry applications. Contains current biomarker guidelines and up-to-date references throughout. Offers a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Contains numerous charts and tables, as well as 1,500 high-quality color histologic images that assist in making a definitive diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
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A Code for Carolyn : A Genomic Thriller
Carolyn’s parents did not, after all, make genomics history by synthesizing her genome in a lab.She has known she is the "Human Hoax" ever since a high school genetics exercise revealed she has trisomy X—a chromosomal abnormality—yet no synthetically constructed genome would have such clear traces of natural conception.Many years later, as molecular biologist, she hopes her colleagues never learn of her embarrassing origins.But when someone ransacks her office and lab, she finds professional embarrassment is the least of her worries.Someone believes she has the results of her parents’ last, secret experiments, and is willing to kill to get them.But all she has from her parents are their genes—can she find what else they may have left her before somebody else does?In a not-so-distant society, where corporations wield as much power as nations and the line between corporate employee and state authority is blurred, the chase is on.Carolyn may have just too little time at hand to unravel the mystery of her parents’ final days and to realize the deep consequences for the future of mankind. This fast-paced novel is followed by an extensive science chapter where the author provides a non-technical primer on modern genetics and on the speculative biology behind Carolyn’s code.
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Mechanisms Driving Karyotype Evolution and Genomic Architecture
Understanding of the origin of species and their adaptability to new environments is one of the main questions in biology. This is fueled by the ongoing debate on species concepts and facilitated by the availability of an unprecedented large number of genomic resources. Genomes are organized into chromosomes, where significant variations in number and morphology are observed among species due to large-scale structural variants such as inversions, translocations, fusions, and fissions. This genomic reshuffling provides, in the long term, new chromosomal forms on which natural selection can act upon, contributing to the origin of biodiversity. This book contains mainly articles, reviews, and an opinion piece that explore numerous aspects of genome plasticity among taxa that will help in understanding the dynamics of genome composition, the evolutionary relationships between species and, in the long run, speciation
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'Superstar DSDS winner'
A "Superstar DSDS winner" refers to a contestant who has won the popular German television show "Deutschland sucht den Superstar" (DSDS), which is the German version of "Pop Idol" or "American Idol." These winners are considered to be the most talented and successful contestants of the season, often receiving a recording contract and opportunities to launch their music career. They are celebrated for their vocal abilities, stage presence, and ability to connect with audiences, making them true superstars in the music industry.
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Sumo or athlete?
It depends on the specific context and criteria being used to make the comparison. Sumo wrestlers are highly skilled athletes who undergo rigorous training and adhere to strict diets in order to compete at the highest level of their sport. They possess incredible strength, agility, and endurance. On the other hand, when comparing sumo to other types of athletes, such as basketball players or soccer players, the physical demands and skills required may be different. Ultimately, both sumo wrestlers and athletes in other sports demonstrate high levels of dedication, discipline, and athleticism in their respective pursuits.
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How can one cement a small podium?
To cement a small podium, you will first need to prepare the area by clearing it of any debris and ensuring it is level. Then, mix the cement according to the instructions on the bag, and pour it into the prepared area. Use a trowel to smooth and level the surface of the cement, and allow it to dry and cure according to the recommended time frame. Once the cement is fully cured, the small podium will be securely cemented in place and ready for use.
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'Victory or Siberia?'
In the context of Russian history, the phrase "Victory or Siberia" refers to the choice faced by soldiers during World War II. It was a common saying that reflected the high stakes of the war, where soldiers believed that they would either achieve victory or face exile to Siberia if they failed. This phrase captures the intense pressure and determination felt by soldiers to win the war at all costs, as the alternative of defeat was seen as a harsh punishment.
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