Products related to RNA:
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RNA Therapeutics : The Evolving Landscape of RNA Therapeutics
RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery.International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function.Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development.
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Applied RNA Bioscience
The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine.It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available.Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production.This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.
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RNA Biology : An Introduction
Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998.Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts, adopting instead a modern approach in both concept and scope.The text is divided into three parts, on mRNA, non-coding RNA, and RNomics, and the author addresses the traditional roles of RNA in the transmission and regulation of genetic information, as well as the recently discovered functions of small RNA species in pathogen defense, cell differentiation and higher-level genomic regulation. All set to become the standard for teaching molecular science to biologists and biochemists.
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Molecular Biology of RNA
RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth.This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme.This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology.Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time.Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics.Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.
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What is RNA self-replication?
RNA self-replication is a process where RNA molecules are able to catalyze their own replication without the need for external enzymes. This ability is crucial for the early evolution of life on Earth, as it is believed to be a key step in the transition from prebiotic chemistry to the emergence of life. RNA self-replication involves the RNA molecule acting as both a template and an enzyme, allowing it to make copies of itself. This process is a fundamental aspect of the RNA world hypothesis, which suggests that RNA played a central role in the origin of life.
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What are DNA and RNA?
DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) are both types of nucleic acids that are essential for the storage and expression of genetic information in living organisms. DNA is the molecule that carries the genetic instructions for the development, functioning, growth, and reproduction of all known living organisms and many viruses. It is a double-stranded molecule that is composed of a long chain of nucleotides. RNA, on the other hand, is a single-stranded molecule that is involved in various biological roles, including coding, decoding, regulation, and expression of genes. It plays a crucial role in the synthesis of proteins from the genetic information encoded in DNA.
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What happens first during RNA processing?
During RNA processing, the initial step is the removal of introns from the pre-mRNA molecule through a process called splicing. This results in the formation of a mature mRNA molecule that only contains exons. Following splicing, a 5' cap is added to the beginning of the mRNA molecule, which helps protect it from degradation and aids in the initiation of translation. Finally, a poly-A tail is added to the 3' end of the mRNA molecule, which also plays a role in stabilizing the mRNA and facilitating its export from the nucleus.
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Is mRNA the same as RNA?
mRNA (messenger RNA) is a type of RNA (ribonucleic acid). RNA is a broad category that includes several types of molecules involved in various cellular processes, including mRNA, tRNA (transfer RNA), and rRNA (ribosomal RNA). mRNA specifically carries the genetic information from the DNA in the cell's nucleus to the ribosomes, where it is used as a template for protein synthesis. Therefore, while mRNA is a type of RNA, not all RNA molecules are mRNA.
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Fields Virology: RNA Viruses
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families.This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesisIncludes two new chapters on SARS - Coronavirus 2 covering both basic science and clinical aspects of CoV2 and COVID-19Covers human immunodeficiency virus (HIV), rotaviruses, respiratory syncytial virus (RSV), measles virus, and moreFeatures more than 400 full-color illustrations, including key figures for use as lecture slidesProvides quick, flexible access to current information both in print and in an improved eBook formatDiscusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency for HIV, and mechanisms of viral oncogenesis for HTLV-1 and HCVNew and forthcoming Field’s Virology volumes, available in print and eBook format:• Emerging Viruses - 2020• DNA Viruses - 2021• RNA Viruses• Fundamental Virology Enrich Your eBook Reading ExperienceRead directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.
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Maison Rna Spacieuse 5 Chambres
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Delphi Gn10324-12B1 12 V Ignition Coil Replaces 30520-Rna-A01 3O52O-Rna-Ao1
Delphi GN10324-12B1 12 V Ignition Coil Replaces 30520-RNA-A01 3O52O-RNA-AO1Delphi Ignition Coils supply the required electrical energy needed to ignite air-fuel mixtures in an engine’s combustion chamber. They are designed to meet a wide variety of continually evolving requirements for combustion calibrations. Delphi Ignition Coils are also designed to operate dependably and reliably under all operating conditions and throughout the entire engine speed range to help manufacturers meet the highest engine performance, exhaust emissions, and fuel economy objectives. Improved dwell accuracy decreases module and coil temperatures for greater reliability Noise abatement material between laminations reduces audible coil noise Early and precise electronic spark timing helps improve fuel economy and provides faster crank-to-run Lower primary inductance provides high-speed performance Coil per cylinder ramp and fire electronics decrease power dissipation and increase efficiency If you are unsure as to whether this is the correct part for your vehicle, please don't hesitate to contact us. Alternatively please use the cross reference table above. Disclaimer: We have taken every care is taken in putting together lists of suitable vehicle compatibilities and component cross references, they are given for general guidance only, and they do not constitute any contractual term, representation or warranty and as such the supplier (Diy Car Service Parts) do not accept any responsibility in respect of any claim whatsoever and howsoever caused arising from the publication of this listing. It remains the responsibility of you (the customer) to check the specification of this item and carefully compare to your original before ordering/installing.
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RNA, the Epicenter of Genetic Information
The origin story and emergence of molecular biology is muddled.The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history.This book documents the many advances, as well as the prejudices and founder fallacies.It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself.Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key FeaturesDocuments the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
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How can one explain RNA interference simply?
RNA interference is a natural process in cells that helps regulate gene expression. It involves small RNA molecules, called siRNAs or miRNAs, binding to specific messenger RNA molecules and targeting them for degradation or blocking their translation into proteins. This process can effectively silence the expression of specific genes, allowing cells to control which proteins are produced. In simple terms, RNA interference can be thought of as a way for cells to turn down the volume on certain genes, reducing their impact on cellular processes.
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How can RNA interference be explained simply?
RNA interference is a natural process in cells that helps regulate gene expression. It involves small RNA molecules, such as siRNA or miRNA, binding to specific messenger RNA molecules and targeting them for degradation. This process helps control the amount of protein produced by a gene, ultimately influencing various cellular functions. In simple terms, RNA interference can be thought of as a way for cells to "silence" certain genes by using small RNA molecules to block their expression.
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Do mutated retrogene also arise from xeno-RNA?
No, mutated retrogene do not arise from xeno-RNA. Mutated retrogene are formed when a processed mRNA transcript is reverse transcribed and integrated back into the genome, leading to a new gene copy. Xeno-RNA, on the other hand, refers to foreign RNA that is introduced into an organism, typically through viral infections or horizontal gene transfer. The two processes are distinct and do not directly lead to the formation of mutated retrogene.
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Do mutated retrogenes also arise from xeno-RNA?
Mutated retrogenes can potentially arise from xeno-RNA, which refers to foreign RNA sequences that are integrated into the genome. Xeno-RNA can be transcribed into DNA by reverse transcriptase enzymes, leading to the formation of retrogenes through the process of retrotransposition. These retrogenes can then undergo mutations and potentially contribute to genetic diversity and evolution. However, the exact mechanisms and frequency of retrogenes arising from xeno-RNA are still being studied.
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